Opioid Growth Factor

**Semantic type:** Pharmacologic Substance

**Definition:** An endogenous pentapeptide with potential antineoplastic and antiangiogenic activities. Opioid growth factor (OGF) binds to and activates the OGF receptor, present on some tumor cells and vascular cells, thereby inhibiting tumor cell proliferation and angiogenesis. (NCI05)

**Synonyms:** - OGF - OGF - opioid growth factor