Sargramostim Plasmid DNA Hepatocellular Carcinoma Vaccine Adjuvant

**Semantic type:** Immunologic Factor|Nucleic Acid, Nucleoside, or Nucleotide|Pharmacologic Substance

**Definition:** A vaccine adjuvant consisting of a plasmid DNA encoding sargramostim (granulocyte-macrophage colony-stimulating factor). Upon administration, expressed sargramostim may stimulate a cytotoxic T cell response enhancing the host immune response to a concomitantly administered hepatocellular carcinoma vaccine. (NCI05)

**Synonyms:** - GM-CSF Plasmid DNA Hepatocellular Carcinoma Vaccine