Yttrium Y-90 Tacatuzumab Tetraxetan

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A radioimmunoconjugate comprised of the humanized monoclonal antibody tacatuzumab, directed against alpha fetoprotein, that is conjugated to the chelating agent tetraxetan and radiolabeled with the beta-emitting radioisotope Yttrium Y 90. Yttrium Y 90 tacatuzumab tetraxetan binds to tumor cells expressing alpha fetoprotein, thereby selectively delivering a cytotoxic dose of beta radiation.

**Synonyms:** - AFP-Cide - Y-90 hAFP-31 - YTTRIUM Y-90 TACATUZUMAB TETRAXETAN - Yttrium (90Y) Tacatuzumab Tetraxetan - Yttrium Y 90 DOTA Monoclonal Antibody HuAFP31 - Yttrium Y 90 Tacatuzumab Tetraxetan - yttrium Y 90 DOTA monoclonal antibody HuAFP31