Yttrium Y-90 Clivatuzumab Tetraxetan

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A radioimmunoconjugate comprised of the humanized monoclonal antibody clivatuzumab, directed against the pancreatic cancer antigen MUC1, that is conjugated to the chelating agent tetraxetan and radiolabeled with the beta-emitting radioisotope Yttrium Y 90. Yttrium Y 90 clivatuzumab tetraxetan binds to tumor cells expressing MUC1 antigen, thereby selectively delivering a cytotoxic dose of beta radiation.

**Synonyms:** - 90Y-hPAM4 - IMMU-107 - YTTRIUM Y-90 CLIVATUZUMAB TETRAXETAN - Yttrium (90Y) Clivatuzumab Tetraxetan - Yttrium Y 90 Clivatuzumab Tetraxetan - Yttrium Y 90 DOTA Monoclonal Antibody HuPAM4 - hPAM4-Cide - hPAM4-DOTA - yttrium Y 90 DOTA monoclonal antibody HuPAM4