Ethacrynic Acid

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** An unsaturated ketone derivative of aryloxyacetic acid without a sulfonamide substituent belonging to the class of loop diuretics. Ethacrynic acid is extensively bound to plasma proteins; both ethacrynic acid in its unchanged form as well as its metabolites are excreted in bile and urine.

**Synonyms:** - EA - ETHACRYNIC ACID - Edecrin - Edecrin - Ethacrynic acid - [2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy]acetic Acid - [2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy]acetic Acid