Dedifferentiated Chordoma

**Semantic type:** Neoplastic Process

**Definition:** A high-grade malignant bone tumor arising from the remnants of the notochord. It is characterized by a lobulated growth pattern, myxoid stroma formation, the presence of physaliphorous cells, and a sarcomatous component.

**Synonyms:** - Dedifferentiated chordoma - Sarcomatoid Chordoma