Signal-Induced Proliferation-Associated Protein 1

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Signal-induced proliferation-associated protein 1 (1042 aa, ~112 kD) is encoded by the human SIPA1 gene. This protein is localized to the nucleus and functions as a GTPase activator for the nuclear Ras-related regulatory proteins.

**Synonyms:** - GTPase-Activating Protein SPA-1 - GTPase-Activating Protein Spa-1 - P130 SPA-1 - SIPA-1 - SIPA-1 Protein - SIPA1 - Sipa-1 - p130 SPA-1