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C49017Level 9

Gardner Fibroma

**Semantic type:** Neoplastic Process

**Definition:** An uncommon, poorly circumscribed, benign neoplasm arising in the soft tissues of infants, children and adolescents. It is characterized by the presence of haphazardly arranged spindle-shaped fibroblasts, collagenous stroma formation, and plaque-like growth pattern. There is a strong genetic component associating the neoplasm with Gardner syndrome and deep fibromatosis/desmoid tumor.

**Synonyms:** - Desmoid Precursor Lesion - Gardner's Fibroma - Gardner-Associated Fibroma

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