Bavituximab

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A chimeric, IgG1 monoclonal antibody directed against anionic phospholipids with potential antineoplastic activity. Bavituximab binds to anionic phospholipids in a beta 2-glycoprotein I-dependent manner, inhibiting tumor growth by stimulating antibody-dependent cellular cytotoxicity (ADCC) to tumor vessels.

**Synonyms:** - BAVITUXIMAB - Chimeric Anti-Phosphotidylserine Monoclonal Antibody - PGN 401 - PGN-401 - PGN401 - Tarvacin