BCHE wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human BCHE wild-type allele is located within 3q26.1-q26.2 and is approximately 65 kb in length. This allele, which encodes cholinesterase protein, plays a role in the hydrolysis of acylcholines. Certain allelic variants of the BCHE gene are responsible for hypocholinesterasemia, resulting in suxamethonium sensitivity and post-anesthetic apnea. Specific inherited defects in this gene are associated with Alzheimer's disease.

**Synonyms:** - Butyrylcholinesterase wt Allele - CHE1 - E1