PLCB3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PLCB3 wild-type allele is located within 11q13 and is approximately 16 kb in length. This allele, which encodes 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 protein, plays a role in the hydrolysis of 1-phosphatidylinositol-4,5 biphosphate. This results in the production of specific second messengers involved in signal transduction.

**Synonyms:** - Phospholipase C, Beta 3 (Phosphatidylinositol-Specific) wt Allele