PLCG2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PLCG2 wild-type allele is located within the vicinity of 16q24.1 and is approximately 179 kb in length. This allele, which encodes 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 2 protein, plays a role in the hydrolysis of 1-phosphatidylinositol-4,5-biphosphate. This results in the production of specific second messengers involved in signal transduction.

**Synonyms:** - APLAID - FCAS3 - PLC-IV - PLC-gamma-2 - PLCgamma2 - Phospholipase C Gamma 2 wt Allele - Phospholipase C, Gamma 2 (Phosphatidylinositol-Specific) wt Allele - Phospholipase C, Gamma-2 Gene - Phospholipase C, Phosphatidylinositol-Specific Gene