FHIT wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human FHIT wild-type allele is located in the vicinity of 3p14.2 and is approximately 1499 kb in length. This allele, which encodes bis(5'-adenosyl)-triphosphatase protein, is involved in the hydrolysis of P1-P3-bis(5'-adenosyl) triphosphate. FHIT gene dysfunction is associated with human cancers including carcinomas of the cervix, esophageus, lung, kidney, and stomach.

**Synonyms:** - AP3Aase - FRA3B - Fragile Histidine Triad Diadenosine Triphosphatase wt Allele - Fragile Histidine Triad Gene