BLM wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human BLM wild-type allele is located in the vicinity of 15q26.1 and is approximately 98 kb in length. This allele, which encodes Bloom syndrome protein, plays a role in the unwinding of single- and double-stranded DNA in a 3'-5' direction during DNA replication and repair. Defects in the BLM gene cause Bloom syndrome.

**Synonyms:** - BS - Bloom Syndrome wt Allele - RECQ2 - RECQL2 - RECQL3