SKIC2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SKIC2 wild-type allele is located in the vicinity of 6p21.33 and is approximately 11 kb in length. This allele, which encodes superkiller complex protein 2, plays a role in exosomal degradation of RNA in the mRNA decay and quality-control pathways. Mutation of the gene is associated with trichohepatoenteric syndrome 2.

**Synonyms:** - 170A - DDX13 - HLP - Helicase SKI2W Gene - SKI2 - SKI2 Homolog, Superkiller Viralicidic Activity 2-Like Gene - SKI2 Subunit of Superkiller Complex Protein Gene - SKI2 Subunit of Superkiller Complex wt Allele - SKI2W - SKIV2 - SKIV2L - SKIV2L1 - Ski2 Like RNA Helicase Gene; Superkiller Viralicidic Activity 2 (S. cerevisiae Homolog)-Like Gene - Superkiller Viralicidic Activity 2-Like (S. cerevisiae) Gene - Superkiller Viralicidic Activity 2-Like Gene - THES2 - W