CDK11B wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CDK11B wild-type allele is located in the vicinity of 1p36.33 and is approximately 31 kb in length. This allele, which encodes cyclin-dependent kinase 11B protein, plays a role in proliferation regulation, apoptosis and is essential for eukaryotic cell cycle control. The allele is deleted or altered frequently in neuroblastoma with amplified MYCN genes.

**Synonyms:** - CDC2L1 - CDK11 - CDK11-p110 - CDK11-p46 - CDK11-p58 - CLK-1 - Cell Division Cycle 2-Like 1 (PITSLRE Proteins) Gene - Cell Division Cycle 2-Like 1 Gene - Cyclin-Dependent Kinase 11B wt Allele - PITSLREA - PK58 - p58 - p58CDC2L1 - p58CLK-1