CDK4 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CDK4 wild-type allele is located within 12q14 and is approximately 4 kb in length. This allele, which encodes cyclin-dependent kinase 4 protein, is involved in the regulation of cell cycle progression from G1/S phase. Variant mutated alleles are associated with tumorigenesis for a variety of cancers.

**Synonyms:** - CMM3 - Cell Division Kinase 4 Gene - Cyclin-Dependent Kinase 4 wt Allele - MGC14458 - PSK-J3