CDKN3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CDKN3 wild-type allele is located within 14q22 and is approximately 23 kb in length. This allele, which encodes cyclin-dependent kinase inhibitor 3 protein, may play a role in cell cycle regulation. Defects in CDKN3 allele have been identified in patients with hepatocellular carcinoma (HCC) and the allele is deleted, mutated, or overexpressed in several kinds of cancers.

**Synonyms:** - CDI1 Gene - CDK2-Associated Dual Specificity Phosphatase Gene - CIP2 Gene - Cyclin-Dependent Kinase Inhibitor 3 (CDK2-Associated Dual Specificity Phosphatase) wt Allele - Cyclin-Dependent Kinase Inhibitor 3 Gene - Cyclin-Dependent Kinase Interacting Protein 2 Gene - Cyclin-Dependent Kinase Interactor 1 Gene - KAP Gene - KAP1 Gene - Kinase-Associated Phosphatase Gene