PTPN11 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PTPN11 wild-type allele is located within 12q24 and is approximately 91 kb in length. This allele, which encodes tyrosine-protein phosphatase non-receptor type 11 protein, is involved in the dephosphorylation of protein-tyrosine phosphates. The PTPN11 gene is associated with severe congenital neutropenia as well as several forms of leukemia.

**Synonyms:** - BPTP3 - CFC - JMML - METCDS - NS1 - PTP-1D - PTP2C - Protein Tyrosine Phosphatase Non-Receptor Type 11 wt Allele - Protein Tyrosine Phosphatase, Non-Receptor Type 11 (Noonan Syndrome 1) Gene - Protein-Tyrosine Phosphatase, Nonreceptor Type, 11 Gene - SH-PTP2 - SH-PTP3 - SHP-2 - SHP2 - SHPTP2