PTPN1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PTPN1 wild-type allele is located within 20q13.1-q13.2 and is approximately 74 kb in length. This allele, which encodes tyrosine-protein phosphatase non-receptor type 1 protein, is involved in the dephosphorylation of protein-tyrosine phosphates. Functional PTPN1 gene polymorphisms are associated with susceptibility to insulin resistance.

**Synonyms:** - PTP-1B - PTP1B - Protein Tyrosine Phosphatase, Non-Receptor Type 1 wt Allele