World Of Taxonomy
C49541Level 4

SKP2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SKP2 wild-type allele is located within 5p13 and is approximately 32 kb in length. This allele, which encodes S-phase kinase-associated protein 2, is involved in cell cycle arrest at the G1/S transition of the cell cycle. SKP2 variant alleles have been established as alleles that are causally involved in the pathogenesis of lymphomas.

**Synonyms:** - FBL1 - FBXL1 - FLB1 - MGC1366 - S-Phase Kinase-Associated Protein 2 wt Allele

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