ADAM11 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ADAM11 wild-type allele is located in the vicinity of 17q21.3 and is approximately 21 kb in length. This allele, which encodes ADAM11 protein, plays a role in integrin binding. Expression of the ADAM 11 gene is disrupted in cancers such as breast and ovarian cancer due to gene rearrangements.

**Synonyms:** - A Disintegrin and Metalloproteinase Domain 11 wt Allele - MDC