CASP6 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CASP6 wild-type allele is located within 4q25 and is approximately 15 kb in length. This allele, which encodes caspase-6 protein, plays a role in the cleavage and activation of both lamins and poly (ADP-ribose) polymerase (PARP) during apoptosis. Overexpression of the CASP6 gene promotes programmed cell death.

**Synonyms:** - Apoptotic Cysteine Protease MCH2 Gene - Apoptotic Protease MCH-2 Gene - CASPASE 6, Apoptosis-Related Cysteine Protease wt Allele - Caspase 6 Gene - Caspase-6 Gene - MCH2