CASP9 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CASP9 wild-type allele is located within 1p36.3-p36.1 and is approximately 32 kb in length. This allele, which encodes caspase-9 protein, is involved in apoptosis via the cleavage and activation of both caspase-3 and poly (ADP-ribose) polymerase (PARP).

**Synonyms:** - APAF-3 - APAF3 - Apoptotic Protease Activating Factor 3 Gene - Apoptotic Protease MCH-6 Gene - CASP-9 - Caspase 9 Gene - Caspase 9, Apoptosis-Related Cysteine Protease wt Allele - Caspase-9 Gene - ICE-LAP6 Gene - ICE-Like Apoptotic Protease 6 Gene - MCH6