ADAM17 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ADAM17 wild-type allele is located within 2p25 and is approximately 66 kb in length. This allele, which encodes ADAM17 protein, is involved in the cleavage of membrane-bound cell-surface proteins to release their mature soluble forms.

**Synonyms:** - A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, Alpha, Converting Enzyme) Gene - A Disintegrin and Metalloproteinase Domain 17 Gene - ADAM Metallopeptidase Domain 17 wt Allele - ADAM18 - CD156B - CSVP - NISBD - NISBD1 - TACE - Tumor Necrosis Factor, Alpha, Converting Enzyme Gene - cSVP