MMP14 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MMP14 wild-type allele is located within 14q11-q12 and is approximately 11 kb in length. This allele, which encodes matrix metalloproteinase-14, plays a role in the activation of progelatinase A. The MMP14 gene is associated with the metastasis of several types of cancer including breast, gastric and laryngeal cancers.

**Synonyms:** - MMP-X1 - MT1-MMP - MTMMP1 - Matrix Metalloproteinase 14 (Membrane-Inserted) wt Allele - Matrix Metalloproteinase 14, Membrane-Type Gene