MMP9 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MMP9 wild-type allele is located within 20q11.2-q13.1 and is approximately 8 kb in length. This allele, which encodes matrix metalloproteinase-9 protein, plays a role in the breakdown of the extracellular matrix via the degradation of both gelatins (types I and V) and interstitial collagens (types IV and V). The MMP9 gene is associated with neoplasm invasiveness.

**Synonyms:** - CLG4B - GELB - Matrix Metalloproteinase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa type IV Collagenase) wt Allele