Chronic Graft Versus Host Disease

**Semantic type:** Disease or Syndrome

**Definition:** A syndrome of immunologically mediated tissue damage that may occur following an allogeneic transplant, and may affect multiple organs with manifestations similar to autoimmune diseases. The onset is usually within three years of transplantation or immunologic manipulation.

**Synonyms:** - Chronic - Chronic GVHD - GVHD, chronic - Graft versus host disease, chronic