PLAU wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PLAU wild-type allele is located within 10q24 and is approximately 6 kb in length. This allele, which encodes urokinase-type plasminogen activator protein, plays a role in the degradation of the extracellular matrix via activation of plasminogen. Overexpression of the PLAU gene is associated with cancer progression.

**Synonyms:** - BDPLT5 - Plasminogen Activator, Urokinase wt Allele - QPD - RP11-417O11.1 - UPA - URK - u-PA