PRTN3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PRTN3 wild-type allele is located in the vicinity of 19p13.3 and is approximately 7 kb in length. This allele, which encodes myeloblastin protein, plays a role in the induction of factor-independent growth of hematopoietic cells. Overexpression of the PRTN3 gene is associated with Wegener granulomatosis.

**Synonyms:** - ACPA - AGP7 - MBN - MBT - PR3 - Proteinase 3 (Serine Proteinase, Neutrophil, Wegener Granulomatosis Autoantigen) wt Allele