GPI wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human GPI wild-type allele is located in the vicinity of 19q13.1 and is approximately 35 kb in length. This allele, which encodes glucose-6-phosphate isomerase protein, is involved in the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. Defects in the GPI gene cause congenital nonspherocytic hemolytic amemia.

**Synonyms:** - AMF - GNPI - Glucose Phosphate Isomerase wt Allele - NLK - PGI - PHI - SA-36 - SA36