TOP1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TOP1 wild-type allele is located within 20q12-q13.1 and is approximately 96 kb in length. This allele, which encodes DNA topoisomerase 1 protein, plays a role in transcriptional enhancement and alteration of single-stranded DNA structure.

**Synonyms:** - DNA Topoisomerase I wt Allele - TOPI - Topoisomerase (DNA) I Gene - Topoisomerase, DNA, I Gene