TOP2A wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TOP2A wild-type allele is located within 17q21-q22 and is approximately 29 kb in length. This allele, which encodes DNA topoisomerase 2-alpha protein, is involved in DNA topology modification, transcriptional activation and chromosome replication.

**Synonyms:** - DNA Topoisomerase II Gene - TOP2 - TP2A - Topoisomerase (DNA) II Alpha 170kDa wt Allele - Topoisomerase, DNA, II, Alpha Gene