Fluoxymesterone

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A halogenated derivative of 17-alpha-methyltestosterone. Similar to testosterone, fluoxymesterone binds to and activates specific nuclear receptors, resulting in an increase in protein anabolism, a decrease in amino acid catabolism, and retention of nitrogen, potassium, and phosphorus. This agent also may competitively inhibit prolactin receptors and estrogen receptors, thereby inhibiting the growth of hormone-dependent tumor lines. Fluoxymesterone is approximately five times more potent than methyltestosterone. (NCI04)

**Synonyms:** - (11Beta,17beta)-9-fluoro-11,17-dihydroxy-17-methylandrost-4-en-3-one - 11Beta,17beta-dihydroxy-9alpha-fluoro-17alpha-methyl-4-androsten-3-one - 9Alpha-fluoro-11beta-hydroxy-17alpha-methyltestosterone - Androfluorene - Androfluorene - Android-F - Androsterolo - Androsterolo - Androxy - FLUOXYMESTERONE - FXM - Halodrin - Halotestin - Halotestin - Ora Testryl - Ora-Testryl - Ora-testryl - Oratestin - Oratestin - Stenox - Testoral - Testoral - Ultandren - Ultandren