NOS1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human NOS1 wild-type allele is located within 12q24.2-q24.31 and is approximately 151 kb in length. This allele, which encodes nitric-oxide synthase, brain protein, is involved in nitric oxide biosynthesis from L-arginine and molecular oxygen. Certain allelic variants of the NOS1 gene are associated with susceptibility to either infantile hypertrophic pyloric stenosis or Parkinson's disease.

**Synonyms:** - IHPS1 - N-NOS - NC-NOS - NOS - NOS-1 - Nitric Oxide Synthase 1 (Neuronal) wt Allele - Nitric Oxide Synthase, Neuronal Gene - bNOS - nNOS