APEX1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human APEX1 wild -type allele is located within 14q11.2-q12 and is approximately 13 kb in length. This allele, which encodes DNA-(apurinic or apyrimidinic site) lyase protein, is involved in DNA repair and the maintenance of DNA integrity.

**Synonyms:** - AP Endonuclease Class I Gene - AP Lyase Gene - APE Gene - APE1 - APEN Gene - APEX Gene - APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 wt Allele - APEX Nuclease (Multifunctional DNA Repair Enzyme) Gene - APX Gene - Apurinic Endonuclease Gene - Apurinic/Apyrimidinic Exonuclease Gene - DNA-(Apurinic or Apyrimidinic Site) Lyase Gene - Deoxyribonuclease (Apurinic or Apyrimidinic) Gene - HAP1 Gene - Human Apurinic Endonuclease 1 Gene - Multifunctional DNA Repair Enzyme Gene - REF-1 Gene - REF1 Gene - Redox Factor 1 Gene