XRCC5 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human XRCC5 wild-type allele is located within 2q35 and is approximately 99 kb in length. This allele, which encodes X-ray repair cross-complementing protein 5, is involved in double-strand break DNA repair and chromosomal translocation. A rare microsatellite polymorphism in this allele is associated with cancer in patients of varying radiosensitivity.

**Synonyms:** - G22P2 - KARP-1 - KARP1 - KU80 - KUB2 - Ku Antigen, 80-Kd Subunit Gene - Ku80 - Ku86 - NFIV - X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) wt Allele - X-Ray Repair, Complementing Defective, In Chinese Hamster, 5 Gene - X-ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining; Ku Autoantigen, 80kDa) Gene