UGT1A1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human UGT1A1 wild-type allele is located in the vicinity of 2q37 and is approximately 13 kb in length. This allele, which encodes UDP-glucuronosyltransferase 1-1 protein, plays a role in the transformation of small lipophilic molecules into water-soluble metabolites. Certain allelic variants of the UGT1A1 gene cause Crigler-Najjar syndrome type I, type II, Gilbert syndrome or transient familial neonatal hyperbilirubinemia.

**Synonyms:** - BILIQTL1 - GNT1 - HUG-BR1 - UDP Glucuronosyltransferase Family 1 Member A1 wt Allele - UDP Glycosyltransferase 1 Family, Polypeptide A1 Gene - UDP glycosyltransferase gene 1 - UDPGT - UDPGT 1-1 - UGT1 - UGT1A - UGT1A1*1 Allele