GSTP1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human GSTP1 wild-type allele is located within 11q13 and is approximately 3 kb in length. This allele, which encodes glutathione S-transferase Pi protein, plays a role in the conjugation of reduced glutathione with both endogenous and exogenous hydrophobic electrophilic compounds. Due to promoter hypermethylation, the GSTP1 gene is not expressed in prostatic intraepithelial neoplasia or prostatic adenocarcinomas.

**Synonyms:** - DFN7 - FAEES3 - Fatty Acid Ethyl Ester Synthase III Gene - Fatty Acid Ethyl Ester Synthase III, Myocardial Gene - GST3 - GST3 Gene - GSTP - GSTP1-1 - GSTPP - Glutathione S-Transferase Pi 1 wt Allele - Glutathione S-Transferase Pi Gene - Glutathione S-Transferase, Pi Gene - HEL-S-22