DNMT3B wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human DNMT3B wild-type allele is located in the vicinity of 20q11.2 and is approximately 47 kb in length. This allele, which encodes DNA (cytosine-5)-methyltransferase 3B protein, plays a role in de novo methylation. Certain allelic variants of the DNMT3B gene cause immunodeficiency-centromeric instability-facial anomalies syndrome.

**Synonyms:** - DNA (Cytosine-5-)-Methyltransferase 3 Beta wt Allele - DNA MTase HsaIIIB Gene - DNA Methyltransferase 3B Gene - DNA Methyltransferase HsaIIIB Gene - ICF Gene - M.HsaIIIB Gene