CRKL wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CRKL wild-type allele is located in the vicinity of 22q11.21 and is approximately 36 kb in length. This allele, which encodes Crk-like protein, is involved in signal transduction. The CRKL gene is overexpressed in certain types of cancer such as breast, colon, lung, ovarian and skin cancer.

**Synonyms:** - V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like wt Allele