PTK2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PTK2 wild-type allele is located within 8q24-qter and is approximately 343 kb in length. This allele, which encodes focal adhesion kinase 1 protein, plays a role in the transduction of adhesion-dependent signals and is involved in adhesion-dependent cell survival signaling. The PTK2 gene is overexpressed in a number of types of cancer such as breast, cervical, colorectal, ovarian, prostate, and thyroid cancers.

**Synonyms:** - FADK - FAK - FAK1 - PTK2 Protein Tyrosine Kinase 2 wt Allele - pp125FAK