FGR wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human FGR wild-type allele is located within 1p36.2-p36.1 and is approximately 23 kb in length. This allele, which encodes proto-oncogene tyrosine-protein kinase FGR protein, is involved in the regulation of outside-in signaling-dependent sustained neutrophil adhesion. Amplification of this gene is associated with the development of hormone-resistant prostate cancer.

**Synonyms:** - Gardner-Rasheed Feline Sarcoma Viral (V-FGR) Oncogene Homolog wt Allele - SRC2 - c-fgr Gene