CD28 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CD28 wild-type allele is located within 2q33 and is approximately 31 kb in length. This allele, which encodes T-cell-specific surface glycoprotein CD28 protein, is involved in the costimulation that is essential for CD4 -positive T-cell proliferation, survival, interleukin-2 production, and T-helper type-2 (Th2) development.

**Synonyms:** - CD28 Antigen (Tp44) Gene - CD28 Molecule wt Allele - T44 - Tp44