YES1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human YES1 wild-type allele is located within 18p11.31-p11.21 and is approximately 91 kb in length. This allele, which encodes proto-oncogene tyrosine-protein kinase Yes protein, plays a role in signal transduction pathways involved in the formation of adherins junctions and gap junctions between cells. Expression of the YES1 gene is up-regulated in colon cancer from patients with inflammatory bowel disease.

**Synonyms:** - HsT441 - P61-YES - YES Proto-Oncogene 1, Src Family Tyrosine Kinase wt Allele - Yes - c-YES Gene - v-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 Gene