ITGAL wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ITGAL wild-type allele is located in the vicinity of 16p11.2 and is approximately 50 kb in length. This allele, which encodes integrin alpha-L protein, plays a role in leukocyte intercellular adhesion and lymphocyte costimulatory signal transduction.

**Synonyms:** - CD11A - Integrin Subunit Alpha L wt Allele - Integrin, Alpha L (Antigen CD11A (p180), Lymphocyte Function-Associated Antigen 1; Alpha Polypeptide) Gene - Integrin, Alpha-L Gene - LFA-1 - LFA1A - Lymphocyte Function-Associated Antigen, Type 1, Alpha Subunit Gene