ITGB2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ITGB2 wild-type allele is located in the vicinity of 21q22.3 and is approximately 35 kb in length. This allele, which encodes integrin beta-2 protein, is involved in cellular adhesion as well as cell-surface mediated signal transduction.

**Synonyms:** - CD18 - Cell Surface Adhesion Glycoprotein (LFA-1/CR3/P150,959 Beta Subunit Precursor) Gene - Complement Component 3 Receptor 3 and 4 Subunit Gene - Integrin Beta Chain, Beta 2 Gene - Integrin Subunit Beta 2 wt Allele - Integrin, Beta 2 (Antigen CD18 (p95), Lymphocyte Function-Associated Antigen 1; Macrophage Antigen 1 (MAC-1) Beta Subunit) Gene - Integrin, Beta 2 (Complement Component 3 Receptor 3 and 4 Subunit) Gene - Integrin, Beta-2 Gene - LAD - LCAMB - LFA-1 - MAC-1 - MF17 - MFI7