PRKG2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PRKG2 wild-type allele is located in the vicinity of 4q13.1-q21.1 and is approximately 116 kb in length. This allele, which encodes cGMP-dependent protein kinase 2 protein, is involved in cGMP-dependent signaling which regulates cellular processes such as cytoskeletal organization and cell motility. The PRKG2 gene is associated with long-term depression.

**Synonyms:** - PRKGR2 - Protein Kinase, cGMP-Dependent, Type II wt Allele - cGK, Type II Gene - cGK2 - cGKII