RYK wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human RYK wild-type allele is located within 3q22 and is approximately 94 kb in length. This allele, which encodes tyrosine-protein kinase RYK protein, plays a role in Wnt-mediated signaling which regulates developmental processes such as cell proliferation, differentiation and epithelial-mesenchymal interactions. The RYK gene is overexpressed in epithelial ovarian cancer.

**Synonyms:** - D3S3195 - RYK Receptor-Like Tyrosine Kinase wt Allele - RYK1