IRAK1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human IRAK1 wild-type allele is located within Xq28 and is approximately 9 kb in length. This allele, which encodes interleukin-1 receptor-associated kinase 1 protein, is involved both in interleukin-1-induced up-regulation of the transcription factor NF-kappa B and in regulation of responsiveness to bacterial endotoxins.

**Synonyms:** - IRAK - Interleukin 1 Receptor Associated Kinase 1 wt Allele - Interleukin-1 Receptor-Associated Kinase 1 Gene - pelle